Letter | Published:

Occurrence of Heterozygotes and Homozygotes for the α-Chain Haemoglobin Variant Hb-J(Tongariki) in New Guinea


THE occurrence of the haemoglobin Hb-J(Tongariki) in new locations in the New Guinea area is of interest because this α-chain variant was the first to be found in Melanesian populations. Furthermore, the high proportion of the variant in heterozygotes and the discovery of three apparently homozygous subjects with Hb-J(Tongariki) as the sole major haemoglobin are relevant to current discussion concerning the possible duplication of the human α-chain gene locus.

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