Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Antibody and Plant Agglutinins stimulate Phagocytosis of Erythrocytes by Acanthamoeba

Nature volume 234, pages 414–415 (1971)Cite this article

Abstract

AXENICALLY grown Acanthamoebae phagocytose in simple media a wide variety of particulates while exercising particle discrimination1, and for studies of particle recognition they provide a useful alternative to vertebrate phagocytes2. We have shown that the uptake of sheep erythrocytes (SE) by the amoebae is increased by antibody to the red cells, as with mammalian macrophages. However, the mechanism of opsonization by antibody seems to differ in this case. Furthermore, ingestion of SE by the amoeba was enhanced by plant agglutinins.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Rabinovitch, M., and De Stefano, M. J., Exp. Cell Res., 64, 275 (1971).

    Article  CAS  Google Scholar 

  2. Rabinovitch, M., in Mononuclear Phagocytes (edit. by Van Furth, R.), 299 (Blackwell, Oxford, 1970).

    Google Scholar 

  3. Neff, R. J., Ray, S. A., Benton, W. F., and Wilborn, M., in Methods in Cell Physiology (edit. by Prescott, D. M.), 1, 55 (Academic Press, New York, 1964).

    Google Scholar 

  4. Weisman, R. A., and Korn, E. D., Biochemistry, 6, 485 (1967).

    Article  CAS  Google Scholar 

  5. Gerisch, O., Luderitz, E., and Rushman, A., Z. Natitrforsch., 22b, 109 (1967).

    Article  CAS  Google Scholar 

  6. Rabinovitch, M., J. Immunol, 99, 1115 (1967).

    CAS  PubMed  Google Scholar 

  7. Olson, M. O., and Lieber, I. E., Biochemistry, 6, 105 (1967).

    Article  CAS  Google Scholar 

  8. Rabinovitch, M., Sem. in Hematol., 5, 134 (1968).

    CAS  Google Scholar 

  9. Mudd, S., McCutcheon, M., and Lucke, B., Physiol. Revs., 14, 210 (1935).

    Article  Google Scholar 

  10. Sachtleben, P., in Cell Electrophoresis (edit. by Ambrose, E. J.), 100 (Little Brown, Boston, 1964).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Cell Biology, New York University School of Medicine, New York, New York, 10016

    M. RABINOVITCH & MARY JO DE STEFANO

Authors
  1. M. RABINOVITCH
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. MARY JO DE STEFANO
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

RABINOVITCH, M., DE STEFANO, M. Antibody and Plant Agglutinins stimulate Phagocytosis of Erythrocytes by Acanthamoeba. Nature 234, 414–415 (1971). https://doi.org/10.1038/234414a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/234414a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing