Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Use of a Sustained-release Multiple Emulsion to Extend the Period of Radioprotection conferred by Cysteamine

Nature volume 234, pages 149–150 (1971)Cite this article

Abstract

PRACTICAL application of the substances which protect biological systems against ionizing radiation has been limited by their toxicity and because they are often metabolized so rapidly that they give protection only for a short time2. We have incorporated the protective chemical cysteamine (mercaptoethylamine, MEA) in a sustained-release multiple emulsion3 in an attempt to extend the duration of protection in mice.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Hollaender, A., Radiation Protection and Recovery (Pergamon, London, 1960).

    Google Scholar 

  2. Bacq, Z. M., Chemical Protection Against Ionising Radiation (Thomas, Springfield, Illinois, 1965).

    Google Scholar 

  3. Collings, A. J., and Schneider, R., Brit. J. Pharmacol., 38, 469P (1970).

    CAS  Google Scholar 

  4. Lajtha, L. G., Seminars Haematol., 4, 293 (1967).

    CAS  Google Scholar 

  5. Till, J. E., and McCulloch, E. A., Radiat. Res., 18, 96 (1963).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Experimental Pathology and Biochemistry, University of Birmingham, Birmingham, B15 2TJ

    PAUL A. GRESHAM, MARION BARNETT & S. VAUGHAN SMITH

  2. Department of Clinical Pharmacology, University of Birmingham, Birmingham, B15 2TJ

    R. SCHNEIDER

Authors
  1. PAUL A. GRESHAM
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. MARION BARNETT
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. S. VAUGHAN SMITH
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. SCHNEIDER
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

GRESHAM, P., BARNETT, M., SMITH, S. et al. Use of a Sustained-release Multiple Emulsion to Extend the Period of Radioprotection conferred by Cysteamine. Nature 234, 149–150 (1971). https://doi.org/10.1038/234149a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/234149a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing