Abstract
Differences have been observed in the thiol sequences of light chains from cardiac and skeletal muscle myosins. Cardiac light chains from both bovine and sheep hearts contain the same thiol sequence (peptide A) which is present in the “alkali” light chains of rabbit and sheep skeletal myosin, but have two extra thiol sequences (peptides B and C). Chemical similarities have been demonstrated between myosin light chains from cardiac and slow skeletal muscle.
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References
Weeds, A. G., and Lowey, S., J. Mol. Biol., (in the press).
Weeds, A. G., Nature, 223, 1362 (1969).
Gaetjens, E., Bárány, K., Bailin, G., Oppenheimer, H., and Bárány, M., Arch. Biochem. Biophys., 123, 82 (1968).
Gershman, L. C., and Dreizen, P., Biochemistry, 9, 1677 (1970).
Perrie, W. T., and Perry, S. V., Biochem. J., 119, 31 (1970).
Gazith, J., Himmelfarb, S., and Harrington, W. F., J. Biol. Chem., 245, 15 (1970).
Kominz, D. R., Carroll, W. R., Smith, E. N., and Mitchell, E. R., Arch. Biochem. Biophys., 79, 191 (1959).
Locker, R. H., and Hagyard, C. J., Arch. Biochem. Biophys., 120, 454 (1967).
Gershman, L. C., Stracher, A., and Dreizen, P., J. Biol. Chem., 244, 2726 (1969).
Lowey, S., and Risby, D., Nature, 234, 81 (1971).
Lowey, S., Slayter, H. S., Weeds, A. G., and Baker, H., J. Mol. Biol., 42, 1 (1969).
Stracher, A., Biochem. Biophys. Res. Commun., 35, 519 (1969).
Dreizen, P., and Gersham, L. C., Biochemistry, 9, 1688 (1970).
Locker, R. H., and Hagyard, C. J., Arch. Biochem. Biophys., 122, 521 (1967).
Tada, M., Bailin, G., Bárány, K., and Bárány, M., Biochemistry, 8, 4842 (1969).
Gray, W. R., in Methods in Enzymology, XI (edit. by Hirs, C. H. W.), 469 (Academic Press, New York, 1967).
Offord, R. E., Nature, 211, 591 (1966).
Brown, J. R., and Hartley, B. S., Biochem. J., 101, 214 (1966).
Weeds, A. G., Biochem. J., 105, 25C (1967).
Weeds, A. G., and Hartley, B. S., Biochem. J., 107, 531 (1968).
Seidel, J. C., J. Biol. Chem., 242, 5623 (1967).
Buller, A. J., in Studies in Physiology (edit. by Curtis, D. R., and McIntyre, A. K.) (Berlin).
Bárány, M., J. Gen. Physiol., 50, 197 (1967).
Buller, A. J., Mommaerts, K. F. H. M., and Seraydarian, K., J. Physiol., 205, 581 (1969).
Sarkar, S., Sreter, F. A., and Gergely, J., Proc. US Nat. Acad. Sci., 68, 946 (1971).
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WEEDS, A., POPE, B. Chemical Studies on Light Chains from Cardiac and Skeletal Muscle Myosins. Nature 234, 85–88 (1971). https://doi.org/10.1038/234085a0
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DOI: https://doi.org/10.1038/234085a0
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