Abstract
Myosin from fast skeletal muscles consists of two large subunits (each about 200,000 daltons) and approximately four smaller subunits (in the range of 20,000 daltons). The light chains are heterogeneous in both size and charge, irrespective of the muscle type of origin. Moreover, the myosins from fast muscles of several species show a characteristic light chain pattern which is distinct from that of slower muscles.
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References
Lowey, S., Slayter, H. S., Weeds, A. G., and Baker, H., J. Mol. Biol., 42, 1 (1969).
Gershman, L. C., Stracher, A., and Dreizen, P., J. Biol. Chem., 244, 2726 (1969).
Gazith, J., Himmelfarb, S., and Harrington, W. F., J. Biol. Chem., 245, 15 (1970).
Kominz, D. R., Carroll, W. R., Smith, E. N., and Mitchell, E. R., Arch. Biochem. Biophys., 79, 191 (1959).
Dreizen, P., Gershman, L. C., Trotta, P. P., and Strachter, A., J. Gen. Physiol., 50, 85 (1967).
Locker, R. H., and Hagyard, C. J., Arch. Biochem. Biophys., 120, 454 (1967).
Gaetjens, E., B´r´ny, K., Baillin, G., Oppenheimer, H., and B´r´ny, M., Arch. Biochem. Biophys., 123, 82 (1968).
Stracher, A., Biochem. Biophys. Res. Commun., 35, 519 (1969).
Dreizen, P., and Gershman, L. C., Biochemistry, 9. 1688 (1970).
Shapiro, A. L., Vinuela, E., and Maizel, jun., J. V., Biochem. Biophys. Res. Commun., 28, 815 (1967).
Weber, K., and Osborn, M., J. Biol. Chem., 244, 4406 (1967).
Reynolds, J. A., and Tanford, C., J. Biol. Chem., 245, 5161 (1970).
Gershman, L. C., and Dreizen, P., Biochemistry, 9, 1677 (1970).
Marshall, J., Conference on Contractility, 47, Pittsburgh, Pennsylvania, 1960.
Weeds, A. G., Nature, 223, 1362 (1969).
Samaha, F. J., Guth, L., and Albers, R. W., J. Biol. Chem., 245, 219 (1970).
Weeds, A. G., and Lowey, S., J. Mol. Biol. (in the press).
Weeds, A. G., Abstracts, Eighth Intern. Cong. Biochem., 29 (1970).
Weeds, A. G., Biochem. J., 105, 25C (1967).
Weeds, A. G., and Pope, B., Nature, 234, 85 (1971).
Frederiksen, D. W., and Holtzer, A., Biochemistry, 7, 3935 (1968).
Voynow, P., and Kurland, C. G., Biochemistry, 10, 517 (1971).
Fazekas de St Groth, S., Webster, R. G., and Daytner, A., Biochim. Biophys. Acta, 71, 377 (1963).
Bárány, M., J. Gen. Physiol., 50, 197 (1967).
Richards, E. G., Chung, C.-S., Menzel, D. B., and Olcott, H. S., Biochemistry, 6, 528 (1967).
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LOWEY, S., RISBY, D. Light Chains from Fast and Slow Muscle Myosins. Nature 234, 81–85 (1971). https://doi.org/10.1038/234081a0
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DOI: https://doi.org/10.1038/234081a0
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