Abstract
MOLECULAR evolution consists of a sequence of events in which originally rare molecular mutants (DNA changes) spread into the species. Two important classes of mutations are nucleotide (or amino-acid) replacement and gene duplication.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
References
Kimura, M., Proc. US Nat. Acad. Sci., 63, 1181 (1969).
Kimura, M., Nature, 217, 624 (1968).
King, J. L., and Jukes, T. H., Science, 164, 788 (1969).
McLaughlin, P. J., and Dayhoff, M. O., in Atlas of Protein Sequence and Structure 1969 (edit. by Dayhoff, M. O.), 39 (National Biomedical Research Foundation, Silver Spring, Maryland, 1969).
Crow, J. F., and Kimura, M., An Introduction to Population Genetics Theory (Harper and Row, New York, 1970).
Dayhoff, M. O., Atlas of Protein Sequence and Structure (National Biomedical Research Foundation, Silver Spring, Maryland, 1969).
Corbin, K. W., and Uzzell, T., Amer. Nat., 104, 37 (1970).
Kimura, M., Jap. J. Genet., 37 (Suppl.), 179 (1961).
Crow, J. F., in Population Biology and Evolution (edit. by Lewontin, R.), 71 (Syracuse University Press, New York, 1968).
Mukai, T., Genetics, 61, 749 (1969).
Kimura, M., and Maruyama, T., Genetics, 54, 1337 (1966).
Muller, H. J., Bull. Amer. Math. Soc., 64, 137 (1958).
Vogel, F., Nature, 201, 847 (1964).
Muller, H. J., Amer. J. Human Genet., 2, 111 (1950).
Mukai, T., Genetics, 50, 1 (1964).
Muller, H. J., in Heritage from Mendel (edit. by Brink, R. A.), 419 (University of Wisconsin Press, Madison, 1967).
Nei, M., Nature, 221, 40 (1969).
Ohno, S., Wolf, U., and Atkin, N. B., Hereditas, 59, 169 (1968).
Kimura, M., Genet. Res., 11, 247 (1968).
Laird, C. D., McConaughy, B. L., and McCarthy, B. J., Nature, 224, 149 (1969).
Walker, P. M. B., Nature, 219, 228 (1968).
Kohn, D. E., Quart. Rev. Biophys., 3 (3), 327 (1970).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
OHTA, T., KIMURA, M. Functional Organization of Genetic Material as a Product of Molecular Evolution. Nature 233, 118–119 (1971). https://doi.org/10.1038/233118a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/233118a0
This article is cited by
-
Very slightly deleterious mutations and the molecular clock
Journal of Molecular Evolution (1987)
-
Towards an alternative evolution model
Acta Biotheoretica (1982)
-
A second purine nucleoside phosphorylase in Escherichia coli K-12
Molecular and General Genetics MGG (1980)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.