Molecular Conformation of Deoxyuridine

Abstract

THE structure determination of deoxyuridine was undertaken as part of a series of conformational studies of nucleic acid components. Such studies give information about the preferred conformation of nucleosides and nucleotides^1,2, and may clarify the conformational differences and changes that occur in nucleic acids. The conformational parameters of interest in deoxyuridine are the pucker of the sugar ring, the torsion angle of the sugar relative to the base about the glycosidic bond and the orientation of the C(5′)–O(5′) bond about the C(4′)–C(5′) bond.