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Lentinan, a New Immuno-accelerator of Cell-mediated Responses


BCG is almost the only agent now used as the immuno-accelerator of cell-mediated responses1'3, but it has various biological side effects and a complicated chemical structure, so that it is not necessarily the most suitable agent. We reported that lentinan4,5 and pachymaran6 strongly inhibited the growth of transplanted tumours in mice, and these two polysaccharides are worth considering as excellent immuno-accelerators.


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MAEDA, Y., CHIHARA, G. Lentinan, a New Immuno-accelerator of Cell-mediated Responses. Nature 229, 634 (1971).

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