Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Cortical Source Locations of Pattern-related Visual Evoked Potentials recorded from the Human Scalp

Abstract

ALTHOUGH there have been many reports about human averaged evoked potentials to visual stimulation, the relation of these scalp-recorded potentials to their underlying sources is obscure, although stimulus-related visual evoked potential (VEP) components are generally thought to originate in the visual cortex. Most cells in the visual cortex of animals such as the cat and monkey are contour-sensitive1–3, and so studies involving patterned or contoured stimulation seem most likely to provide such information. I report here some preliminary results which illustrate the great influence of the location of a retinal stimulus on the characteristics of pattern-related VEPs, and indicate how such studies provide clues to the probable location of the sources of different components of these VEPs.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Hubel, D. H., and Wiesel, T. N., J. Physiol., 160, 106 (1962).

    Article  CAS  Google Scholar 

  2. Hubel, D. H., and Wiesel, T. N., J. Neurophysiol., 28, 229 (1965).

    Article  CAS  Google Scholar 

  3. Hubel, D. H., and Wiesel, T. N., J. Physiol., 195, 215 (1968).

    Article  CAS  Google Scholar 

  4. Rietveld, W. J., Tordoir, W. E. M., Hagenouw, J. R. B., and van Dolgen, K. J., Acta Physiol. Pharmacol. Neerl., 13, 340 (1965).

    CAS  PubMed  Google Scholar 

  5. Schreinemachers, H. P., and Henkes, H. E., Ophthalmologica, 155, 17 (1968).

    Article  CAS  Google Scholar 

  6. Rémond, A., Lesèvre, N., and Torres, F., Rev. Neurol., 113, 193 (1965).

    PubMed  Google Scholar 

  7. Jeffreys, D. A., Neurosciences Res. Prog. Bull., 7, 211 (1969).

    Google Scholar 

  8. Halliday, A. M., and Michael, W. F., J. Physiol., 208, 499 (1970).

    Article  CAS  Google Scholar 

  9. van der Tweel, L. H., Regan, D., and Spehreijse, H., Proc. Seventh Intern. Symp. ISCERG (in the press).

  10. Jeffreys, D. A., Electroenceph. Clin. Neurophysiol., 29, 328 (1970).

    CAS  PubMed  Google Scholar 

  11. Holmes, G., Proc. Roy. Soc., B. 132, 348 (1945).

    Article  ADS  Google Scholar 

  12. Teuber, H. L., Battersby, W. S., and Bender, M. B., Visual Defects after Penetrating Missile Wounds of the Brain (Harvard University Press, Cambridge, Massachusetts, 1960).

    Book  Google Scholar 

  13. Brindley, G. S., and Lewin, W. S., J. Physiol., 196, 479 (1968).

    Article  CAS  Google Scholar 

  14. Polyak, S., The Vertebrate Visual System (University of Chicago Press, Chicago, 1957).

    Google Scholar 

  15. Talbot, S. A., and Marshall, W. H., Amer. J. Ophthalmol., 24, 1255 (1941).

    Article  Google Scholar 

  16. Daniel, D. M., and Whitteridge, D., J. Physiol., 159, 203 (1961).

    Article  CAS  Google Scholar 

  17. Myers, R. E., J. Comp. Neurol., 118, 1 (1962).

    Article  CAS  Google Scholar 

  18. Cowey, A., J. Neurophysiol., 27, 366 (1964).

    Article  CAS  Google Scholar 

  19. Cragg, B. G., Vision Res., 9, 733 (1969).

    Article  CAS  Google Scholar 

  20. Zeki, S. M., Brain Res., 14, 271 (1969).

    Article  CAS  Google Scholar 

  21. Rolls, E. T., and Cowey, A., Exp. Brain Res., 10, 298 (1970).

    Article  CAS  Google Scholar 

  22. Fourment, A., Jami, A., Carter, J., and Scheiner, J., Electroenceph. Clin. Neurophysiol., 19, 217 (1965).

    Article  CAS  Google Scholar 

  23. Vaughan, H. G., Electroenceph. Clin. Neurophysiol., 25, 1 (1968).

    Article  Google Scholar 

  24. Vaughan, H.G., and Ritter, W., Electroenceph. Clin. Neurophysiol., 28, 360 (1970).

    Article  Google Scholar 

  25. Schneider, M., and Gerin, P., Electroenceph. Clin. Neurophysiol., 28, 69 (1970).

    Article  CAS  Google Scholar 

  26. Shaw, J. C., and Roth, M., Electroenceph. Clin. Neurophysiol., 7, 285 (1955).

    Article  CAS  Google Scholar 

  27. Rush, S., and Driscoll, D. A., IEEE Trans. Bio-med. Engng., 16, 15 (1969).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

JEFFREYS, D. Cortical Source Locations of Pattern-related Visual Evoked Potentials recorded from the Human Scalp. Nature 229, 502–504 (1971). https://doi.org/10.1038/229502a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/229502a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing