Abstract
THE effect of adrenaline on carbohydrate metabolism in liver has been intensively investigated 1–3. On the other hand, very little is known about the role of acetylcholine4. The observation of Shimazu5 on the increase of the activity of liver glycogen synthetase after vagal stimulation induced us to investigate the possible effect of acetylcholine on carbohydrate metabolism in the isolated perfused rat liver. Part of the present results was reported elsewhere6.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Miller, L. L., Fed. Proc., 24, 737 (1965).
Shimassek, H., and Mitzkat, H. J., Biochem. Z., 337, 510 (1963).
Lundholm, L., Mohme Lundholme, E., and Svedmyr, N., in The Biological Basis of Medicine, 2, (edit. by Bittar, E. E. and Bittar, N.), 101 (Academic Press, New York, 1968).
Ellis, S., Kennedy, B. L., Eusebi, A. J., and Vincent, N. H., Ann. NY Acad. Sci., 139, 826 (1967).
Shimazu, T., Science, 156, 1256 (1967).
Ottolenghi, C., and Caniato, A., Boll. Soc. Ital. Biol. Sper., 46, 8 (1970).
Miller, L. L., Bly, C. G., Watson, M. L., and Bale, W. F., J. Exp. Med., 94, 431 (1951).
Spies, J. R., in Methods in Enzymology, 3, (edit. by Colowick, S. P. and Kaplan, N. O.), 467 (Academic Press, New York, 1957).
Hassid, W. Z., and Abraham, S., in Methods in Enzymology, 3, (edit. by Colowick, S. P. and Kaplan, N. O.), 34 (Academic Press, New York, 1957).
Villar-Palasi, C., Rosell-Perez, M., Hizukuri, S., Huijing, F., and Larner, J., in Methods in Enzymology, 3, (edit. by Colowick, S. P. and Kaplan, N. O.), 374 (Academic Press, New York, 1967).
Glinsman, W., Pauk, G., and Hern, E., Biochem. Biophys. Res. Commun., 39, 774 (1970).
Hers, H. G., and Van Hoof, F., in Methods in Enzymology, 8, (edit. by Colowick, S. P. and Kaplan, N. O.), 525 (Academic Press, New York, 1967).
Staib, W., Staib, R., Hermann, J., and Meiers, H. G., in Stoffwechsel der Isolierf Perfundierted Leber (edit. by Staib, W. and Scholz, R.), 155 (Springer Verlag, Berlin, 1967).
Buschiazzo, H., Exton, J. H., and Park, C. R., Proc. US Nat. Acad. Sci., 65, 383 (1970).
De Wulf, H., and Hers, H. G., Europ. J. Biochem., 6, 558 (1968).
Shimazu, T., and Amakawa, A., Biochim. Biophys. Acta, 165, 335 (1968).
Shimazu, T., and Amakawa, A., Biochim. Biophys. Acta, 165, 349 (1968).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
OTTOLENGHI, C., CANIATO, A. & BARNABEI, O. Effect of Acetylcholine on Glycogen Formation and the Activity of Glycogen Synthetase in Isolated, Perfused Rat Liver. Nature 229, 420–422 (1971). https://doi.org/10.1038/229420a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/229420a0
This article is cited by
-
Central nervous system regulation of liver and adipose tissue metabolism
Diabetologia (1981)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
