Abstract
MUCH circumstantial evidence implicates protein and RNA synthesis in memory consolidation and increasing interest in work directed toward elucidating the macromolecular chemical processes underlying learning1,2. A derepression model has been advocated by Bonner3, who also suggested a method by which the model might be tested. Newly induced RNA molecules would be gene products, present in the brains of learning animals but not naive animals, and they should be able to be pulse labelled and detected by competitive hybridization experiments.
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VON HUNGEN, K. Competitive Hybridization with Brain RNA fails to confirm New RNA induced by Learning. Nature 229, 114–115 (1971). https://doi.org/10.1038/229114b0
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DOI: https://doi.org/10.1038/229114b0
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