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New RNA Polymerase from Escherichia coli infected with Bacteriophage T7

Abstract

A new T7-specific RNA polymerase is found in T7 phage-infected cells. It is the product of T7 gene I and is physically and biochemically distinct from the host cell RNA polymerase. The synthesis of T7 RNA polymerase provides a direct explanation for the pleiotropic control of late T7 functions exerted by gene I.

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CHAMBERLIN, M., MCGRATH, J. & WASKELL, L. New RNA Polymerase from Escherichia coli infected with Bacteriophage T7. Nature 228, 227–231 (1970). https://doi.org/10.1038/228227a0

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