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Use of Transient Optical Rotation for Biopolymer Characterization

Abstract

THE optical activity of macromolecules has long been recognized as a valuable indicator of certain molecular properties. Studies were initially made of the optical rotation of macromolecular solutions, that is, their ability to rotate the plane of polarization of incident plane-polarized light, at a single wavelength. Measurements were later extended to a variety of wavelengths so as to observe the dispersion of the optical rotation with wavelength, that is, optical rotatory dispersion (ORD).

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JENNINGS, B., BAILY, E. Use of Transient Optical Rotation for Biopolymer Characterization. Nature 228, 1309–1311 (1970). https://doi.org/10.1038/2281309a0

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