Abstract
HAEMOPOIETIC stem cells, characterized by their ability to differentiate and reproduce themselves, are believed to be precursors of all differentiated blood cells in the organism. During embryogenesis, they are presumably present in the yolk sac, liver, spleen and marrow—the successive sites of erythropoiesis. The stem cells may be derived from a common source or they may arise independently in each site during development. If they are not indigenous to the erythropoietic organ they may be either transported from one site to another through the peripheral blood1 or incorporated into the developing organ in tissues shared by the previous erythroid site2,3.
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BARKER, J. Embryonic Mouse Peripheral Blood Colony-forming Units. Nature 228, 1305–1306 (1970). https://doi.org/10.1038/2281305a0
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DOI: https://doi.org/10.1038/2281305a0
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