Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Stimulation of Proliferation of 19S Antibody-forming Cells in the Spleens of Immunized Guinea-pigs after Exchange Transfusion

Abstract

THERE is abundant evidence that the immune response, both primary (19S) and secondary (7S), is regulated by a feed-back mechanism involving serum antibody, particularly 7S antibody1–4, but the exact mechanism remains unclear.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Uhr, J. W., and Baumann, J. B., J. Exp. Med., 113, 935 (1961).

    Article  CAS  Google Scholar 

  2. Wigzen, H., Cold Spring Harbor Symp. Quant. Biol., 32, 507 (1967).

    Article  Google Scholar 

  3. Jerne, N. K., Cold Spring Harbor Symp. Quant. Biol., 32, 591 (1967).

    Article  CAS  Google Scholar 

  4. Uhr, J. W., and Möller, G., Adv. Immunol., 8, 81 (1968).

    Article  CAS  Google Scholar 

  5. Rowley, D. A., and Fitch, F. W., J. Exp. Med., 120, 987 (1964).

    Article  CAS  Google Scholar 

  6. Möller, G., J. Exp. Med., 127, 291 (1968).

    Article  Google Scholar 

  7. Pierce, C. W., J. Exp. Med., 130, 365 (1969).

    Article  CAS  Google Scholar 

  8. Jerne, N. K., and Nordin, A. A., Science, 140, 405 (1963).

    Article  ADS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

STURGILL, B., WORZNIAK, M. Stimulation of Proliferation of 19S Antibody-forming Cells in the Spleens of Immunized Guinea-pigs after Exchange Transfusion. Nature 228, 1304–1305 (1970). https://doi.org/10.1038/2281304a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/2281304a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing