Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Mixed Lymphocyte Cultures and HL-A Identity in Unrelated Subjects

Nature volume 228, pages 63–65 (1970)Cite this article

Abstract

INVESTIGATIONS using highly selected lymphocytotoxic and complement-fixing platelet antibodies have made it possible to define a considerable number of antigens belonging to the HL-A system. These antisera are determined by genetic information belonging to a still unknown number of closely linked loci, subloci or mutational sites. Most of the known HL-A antigens seem to belong to two series, ‘LA’ and ‘4’, each of which contains a number of mutually exclusive genes and corresponding antigens. An ever increasing number of antigens are being identified1–5. The various genes and corresponding antigens, which can be determined, are given in Table 1.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Kissmeyer-Nielsen, F., Svejgaard, A., and Hauge, M., Nature, 219, 1116 (1968).

    Article  ADS  CAS  Google Scholar 

  2. Kissmeyer-Nielsen, F., Svejgaard, A., and Hauge, M., Transplant. Proc., 1, 357 (1969).

    CAS  PubMed  Google Scholar 

  3. Kissmeyer-Nielsen, F., Nielsen, L. Staub, Nielsen, Sandberg L., Svejgaard, A., and Thorsby, E., in Histocompatibility Testing 1970, 105 (Munksgaard, Copenhagen, 1970).

    Google Scholar 

  4. Svejgaard, A., Kissmeyer-Nielsen, F., and Thorsby, E., in Histocompatibility Testing 1970, 153 (Munksgaard, Copenhagen, 1970).

    Google Scholar 

  5. Thorsby, E., Kissmeyer-Nielsen, F., and Svejgaard, A., in Histocompatibility Testing 1970, 137 (Munksgaard, Copenhagen, 1970).

    Google Scholar 

  6. Amos, D. B., and Bach, F. H., J. Exp. Med., 128, 623 (1968).

    Article  CAS  Google Scholar 

  7. Kissmeyer-Nielsen, F., and Kjerbye, K. E., Histocompatibility Testing 1967, 381 (Munksgaard, Copenhagen, 1967).

    Google Scholar 

  8. Svejgaard, A., and Kissmeyer-Nielsen, F., Vox Sang., 14, 106 (1968).

    Article  CAS  Google Scholar 

  9. Sørensen, S. F., and Kissmeyer-Nielsen, F., Acta Path. Microbiol. Scand., 77, 117 (1969).

    Article  Google Scholar 

  10. Sørensen, S. F., Andersen, V., and Giese, J., Acta Path. Microbiol. Scand., 75, 508 (1969).

    PubMed  Google Scholar 

  11. Rapaport, F. T., Thomas, L., Converse, J. M., and Lawrence, H. S., Ann. NY Acad. Sci., 87, 217 (1960).

    Article  ADS  CAS  Google Scholar 

  12. Sørensen, S. F., Andersen, V., and Giese, J., Acta Path. Microbiol. Scand., 76, 259 (1969).

    Article  Google Scholar 

  13. Svejgaard, A., and Kissmeyer-Nielsen, F., Nature, 219, 868 (1968).

    Article  ADS  CAS  Google Scholar 

  14. Thorsby, E., Kissmeyer-Nielsen, F., Sandberg, L., and Lindholm, A., Scand. J. Haematol., 7, 195 (1970).

    Article  CAS  Google Scholar 

  15. Ceppellini, R., Mattiuz, P. L., Scudeller, G., and Visetti, M., Transplant. Proc., 1, 385 (1969).

    CAS  PubMed  Google Scholar 

  16. Rood, J. J. van, and Eijsvoogel, V. P., Lancet, i, 690 (1970).

Download references

Author information

Authors and Affiliations

  1. Blood Bank and Blood Grouping Laboratory, University Hospital of Århus, Århus C, 8000, Denmark

    F. KISSMEYER-NIELSEN & A. SVEJGAARD

  2. University Hospital of Copenhagen, Medical Department P and Institute for Experimental Immunology, University of Copenhagen, Copenhagen, 2100, Denmark

    S. FREIESLEBEN SØRENSEN

  3. Blood Bank and Blood Grouping Laboratory, University Hospital of Copenhagen,

    L. STAUB NIELSEN

  4. Blood Bank and Department of Immunohaematology, Ullevål Hospital, Oslo, 1, Norway

    E. THORSBY

Authors
  1. F. KISSMEYER-NIELSEN
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. SVEJGAARD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. S. FREIESLEBEN SØRENSEN
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. L. STAUB NIELSEN
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. E. THORSBY
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

KISSMEYER-NIELSEN, F., SVEJGAARD, A., SØRENSEN, S. et al. Mixed Lymphocyte Cultures and HL-A Identity in Unrelated Subjects. Nature 228, 63–65 (1970). https://doi.org/10.1038/228063a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/228063a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing