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Lymphocyte Stimulation in Pigs: Evidence for the Existence of a Single Major Histocompatibility Locus, PL-A

Abstract

IN those species which have been sufficiently studied there is evidence of a single major histocompatibility locus (man, mouse, rat, chicken) that plays a predominant part in graft rejection. We present evidence for the existence of such a major locus in pigs by using the mixed lymphocyte reaction1,2.

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References

  1. Bach, F. H., Albertini, R. J., Klostermann, H. G., and Day, G. E., Histocompahbility Testing, (edit. by Curtoni, E. S., Mattiuz, P. L., and Tozi R. M.), chap. 55 (Munksgaard, Copenhagen, 1967).

    Google Scholar 

  2. Bach, F. H., Albertini, R. J., Amos, D. B., Ceppellini, R., Mattiuz, P. L., and Miggiano, V. C., Transplant. Proc., 1, 339 (1969).

    CAS  PubMed  Google Scholar 

  3. Viza, D. C., Experientia, 23, 848 (1967).

    Article  CAS  Google Scholar 

  4. Boylston, A. W., Guttmann, R. D., and Merrill, J. P., Intern. Arch. Allergy, 34, 339 (1968).

    Article  CAS  Google Scholar 

  5. Viza, D. C., Degani, Ora, Dausset, J., and Davies, D. A. L., Nature, 219 704 (1968).

    Article  ADS  CAS  Google Scholar 

  6. Rychlikova, M., and Ivanyi, P., Folia Biol., 15, 126 (1969).

    CAS  Google Scholar 

  7. Calne, R. Y., Sells, R. A., Pena, J. R., Davis, D. R., Millard, P. R., Herbetson, B. M., Binns, R. M., and Davies, D. A. L., Nature, 223, 472 (1969).

    Article  ADS  CAS  Google Scholar 

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VIZA, D., SUGAR, J. & BINNS, R. Lymphocyte Stimulation in Pigs: Evidence for the Existence of a Single Major Histocompatibility Locus, PL-A. Nature 227, 949–950 (1970). https://doi.org/10.1038/227949a0

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