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Factor Dependent Binding of Methionyl-tRNAs to Reticulocyte Ribosomes

Abstract

Reticulocyte initiation factors bind a formylatable methionine tRNA but not a non-formylatable tRNA. Elongation factors bind only the non-formylatable species. These findings suggest that haemoglobin chains may be initiated in a way similar to bacterial proteins.

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SHAFRITZ, D., ANDERSON, W. Factor Dependent Binding of Methionyl-tRNAs to Reticulocyte Ribosomes. Nature 227, 918–920 (1970). https://doi.org/10.1038/227918a0

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