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RNA Polymerase Mutants blocked in Sporulation

Abstract

A class of RNA polymerase mutants of B. subtilis fails to sporulate. The same mutational alteration prevents the change in template specificity of the enzyme characteristic of sporulating wild-type cells, suggesting that this change plays an essential part in the sporulation process.

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References

  1. Travers, A. A., Nature, 223, 1107 (1969).

    Article  ADS  CAS  Google Scholar 

  2. Travers, A. A., Nature, 225, 1009 (1970).

    Article  ADS  CAS  Google Scholar 

  3. Losick, R., and Sonenshein, A. L., Nature, 224, 35 (1969).

    Article  ADS  CAS  Google Scholar 

  4. Sonenshein, A. L., and Roscoe, D. H., Virology, 39, 265 (1969).

    Article  CAS  Google Scholar 

  5. Bach, M., and Gilvarg, C., J. Biol. Chem., 241, 4563 (1966).

    CAS  Google Scholar 

  6. Deutscher, M. P., and Kornberg, A., J. Biol. Chem., 243, 4653 (1968).

    CAS  Google Scholar 

  7. Burgess, R. R., Travers, A. A., Dunn, J. J., and Bautz, E. K. F., Nature, 221, 43 (1969).

    Article  ADS  CAS  Google Scholar 

  8. Losick, R., Shorenstein, R. G., and Sonenshein, A. L., Nature, 227, 910 (1970) (following article).

    Article  ADS  CAS  Google Scholar 

  9. Kerjan, P., and Szulmajster, J., FEBS Letters, 5, 288 (1969).

    Article  CAS  Google Scholar 

  10. Avila, J., Hermoso, J. M., Vinuela, E., and Salas, M., Nature, 226, 1244 (1970).

    Article  ADS  CAS  Google Scholar 

  11. diMauro, E., Snyder, L., Marino, P., Lamberti, A., Coppo, A., and Tocchini-Valentini, G. P., Nature, 222, 533 (1969).

    Article  ADS  CAS  Google Scholar 

  12. Geiduschek, E. P., and Sklar, J., Nature, 221, 883 (1969).

    Article  ADS  Google Scholar 

  13. Schaeffer, P., and Ionesco, H., CR Acad. Sci., 251, 3125 (1960).

    CAS  Google Scholar 

  14. Schaeffer, P., Ionesco, H., and Jacob, F., CR Acad. Sci., 249, 577 (1959).

    Google Scholar 

  15. Tamir, H., and Gilvarg, C., J. Biol. Chem., 241, 1895 (1966).

    Google Scholar 

  16. Hall, D. H., Proc. US Nat. Acad. Sci., 58, 584 (1967).

    Article  ADS  CAS  Google Scholar 

  17. Schaeffer, P., Ionesco, H., Ryter, A., and Balassa, G., Colloq. Intern. CNRS, Marseille, 124, 553 (1963).

    Google Scholar 

  18. Wehrli, W., and Staehelin, M., in Lepetit Colloq. Biol. Med., 1, 65 (1970).

    Google Scholar 

  19. Rabussay, D., and Zillig, W., FEBS Letters, 5, 104 (1969).

    Article  CAS  Google Scholar 

Download references

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SONENSHEIN, A., LOSICK, R. RNA Polymerase Mutants blocked in Sporulation. Nature 227, 906–909 (1970). https://doi.org/10.1038/227906a0

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