Letter | Published:

Monosodium Glutamate and the Chinese Restaurant Syndrome

Nature volume 227, pages 611612 (08 August 1970) | Download Citation

Subjects

Abstract

IT has been suggested1–4 that monosodium glutamate (MSG) is responsible for the “Chinese restaurant syndrome”—a burning sensation in the back of the neck spreading to the forearms and to the anterior thorax, accompanied by a feeling of infraorbital pressure, tightness and substernal discomfort. But no study of this phenomenon involved a double blind technique, or any other experimental condition which can be used to assess the significance of subjective reactions.

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References

  1. 1.

    , New Engl. J. Med., 278, 796 (1968).

  2. 2.

    , and , New Engl. J. Med., 279, 105 (1968).

  3. 3.

    , , , and , New Engl. J. Med., 279, 105 (1968).

  4. 4.

    , , , and , Science, 163, 826 (1969).

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Author information

Affiliations

  1. Istituto di Ricerche Farmacologiche, “Mario Negri”, Via Eritrea, 62, 20157 Milano, Italy.

    • P. L. MORSELLI
    •  & S. GARATTINI

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DOI

https://doi.org/10.1038/227611a0

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