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Monosodium Glutamate and the Chinese Restaurant Syndrome

Abstract

IT has been suggested1–4 that monosodium glutamate (MSG) is responsible for the “Chinese restaurant syndrome”—a burning sensation in the back of the neck spreading to the forearms and to the anterior thorax, accompanied by a feeling of infraorbital pressure, tightness and substernal discomfort. But no study of this phenomenon involved a double blind technique, or any other experimental condition which can be used to assess the significance of subjective reactions.

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References

  1. 1

    Man-Kwdk, R. Ho, New Engl. J. Med., 278, 796 (1968).

    Google Scholar 

  2. 2

    Schaumburg, H. H., and Byck, R., New Engl. J. Med., 279, 105 (1968).

    CAS  Article  Google Scholar 

  3. 3

    Abos, M., Leavitt, M. R., Marmorek, L., and Wolschina, S. B., New Engl. J. Med., 279, 105 (1968).

    Article  Google Scholar 

  4. 4

    Schaumburg, H. H., Byck, R., Gerstl, G., and Mashman, J. H., Science, 163, 826 (1969).

    ADS  CAS  Article  Google Scholar 

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MORSELLI, P., GARATTINI, S. Monosodium Glutamate and the Chinese Restaurant Syndrome. Nature 227, 611–612 (1970). https://doi.org/10.1038/227611a0

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