Abstract
ANTILYMPHOCYTIC serum (ALS) is widely known for its ability to impair immunological responsiveness, especially of cell-mediated immunity1,2. The main immunosuppressive component of ALS in vivo is IgG (7S-γ) immunoglobulin3,4. Administration of ALS to animals also causes a marked reduction in inflammation, as judged by various experimental models5–7, without causing increased adrenal activity5,6.
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BILLINGHAM, M., ROBINSON, B. & GAUGAS, J. Two Anti-inflammatory Components in Antilymphocytic Serum. Nature 227, 276–277 (1970). https://doi.org/10.1038/227276a0
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DOI: https://doi.org/10.1038/227276a0
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