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Presence of EB Virus Nucleic Acid Homology in a “Virus-free” Line of Burkitt Tumour Cells

Abstract

The presence of virus in Burkitt lymphoma cells is hard to confirm, but small amounts of viral DNA have now been revealed by hybridization with DNA from cells of the Raji line of the tumour.

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References

  1. Burkitt, D., Brit. J. Surg., 56, 218 (1958).

    Article  Google Scholar 

  2. Burkitt, D., and Davies, J. N. P., Med. Press, 245, 367 (1961).

    Google Scholar 

  3. Epstein, M. A., Achong, B. G., and Barr, Y. M., Lancet, i, 702 (1964).

  4. Henle, G., and Henle, W., J. Bact., 91, 1248 (1966).

    CAS  PubMed  PubMed Central  Google Scholar 

  5. Henle, W., and Henle, G., Perspectives in Virology, 6, 105 (1968).

    Google Scholar 

  6. Gerber, P., and Birch, S. M., Proc. US Nat. Acad. Sci., 58, 478 (1967).

    Article  ADS  CAS  Google Scholar 

  7. Henle, G., and Henle, W., Trans. NY Acad. Sci., 29, 71 (1966).

    Article  CAS  Google Scholar 

  8. Henle, G., and Henle, W., Cancer Res., 27, 2442 (1967).

    CAS  PubMed  Google Scholar 

  9. Klein, G., Pearson, G., Henle, G., Henle, W., Diehl, V., and Niederman, J. C., J. Exp. Med., 128, 1021 (1968).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Klein, G., Clifford, P., Klein, E., Smith, R. T., Minowada, J., Kourilski, F. M., and Burchenal, J. H., J. Nat. Cancer Inst., 39, 1027 (1967).

    CAS  PubMed  Google Scholar 

  11. Old, L. J., Boyse, E. A., Oettgen, H. F., de Harven, E., Geering, G., Williamson, B., and Clifford, P., Proc. US Nat. Acad. Sci., 56, 1699 (1966).

    Article  ADS  CAS  Google Scholar 

  12. Henle, G., Henle, W., and Diehl, V., Proc. US Nat. Acad. Sci., 59, 94 (1968).

    Article  ADS  CAS  Google Scholar 

  13. Niederman, J. C., McCollum, R. W., Henle, G., and Henle, W., J. Amer. Med. Assoc., 203, 205 (1968).

    Article  CAS  Google Scholar 

  14. Weinberg, A., and Becker, Y., Virology, 39, 312 (1969).

    Article  CAS  PubMed  Google Scholar 

  15. Schulte-Holthausen, H., and zur Hausen, H., Virology, 40, 776 (1970).

    Article  CAS  PubMed  Google Scholar 

  16. Pulvertaft, R. J. V., Lancet, i, 238 (1964).

  17. Epstein, M. A., Achong, B. G., Barr, Y. M., Zajac, B., Henle, G., and Henle, W., J. Nat. Cancer Inst., 37, 547 (1966).

    CAS  PubMed  Google Scholar 

  18. Pope, J. H., Horne, M. K., and Wetters, E. J., Nature, 222, 186 (1969).

    Article  ADS  CAS  PubMed  Google Scholar 

  19. Hinuma, Y., Konn, M., Yamaguchi, J., Wudarski, W. J., Blakeslee, D. R., and Grace, J. T., J. Virol., 1, 1045 (1967).

    CAS  PubMed  PubMed Central  Google Scholar 

  20. Diamond, L., Intern. J. Cancer, 2, 143 (1967).

    Article  CAS  Google Scholar 

  21. zur Hausen, H., Henle, W., Hummeler, K., Diehl, V., and Henle, G., J. Virol., 1, 830 (1967).

    CAS  PubMed  PubMed Central  Google Scholar 

  22. zur Hausen, H., J. Virol., 2, 218 (1968).

    CAS  PubMed  PubMed Central  Google Scholar 

  23. Iwakata, S., and Grace, J. T., NY State J. Med., 64, 2279 (1964).

    Google Scholar 

  24. Clarkson, B., Strife, A., and de Harven, E., Cancer, 20, 926 (1967).

    Article  CAS  PubMed  Google Scholar 

  25. zur Hausen, H., and Sokol, F., J. Virol., 4, 256 (1969).

    CAS  PubMed  PubMed Central  Google Scholar 

  26. Warner, J. R., Soeiro, E., Birnboim, H. C., Girard, M., and Darnell, J. E., J. Mol. Biol., 19, 349 (1966).

    Article  CAS  PubMed  Google Scholar 

  27. Aloni, Y., Winocour, E., and Sachs, L., J. Mol. Biol., 31, 415 (1968).

    Article  CAS  PubMed  Google Scholar 

  28. Fujinaga, K., and Green, M., Proc. US Nat. Acad. Sci., 55, 1567 (1966).

    Article  ADS  CAS  Google Scholar 

  29. Warner, J. R., Knopf, P., and Rich, A., Proc. US Nat. Acad. Sci., 49, 122 (1963).

    Article  ADS  CAS  Google Scholar 

  30. Martin, R. G., and Ames, B. N., J. Biol. Chem., 236, 1372 (1961).

    CAS  PubMed  Google Scholar 

  31. Vendrely, R., and Vendrely, C., Bull. Biol. France Belg., 86, 1 (1952).

    CAS  Google Scholar 

  32. Russel, W. C., and Crawford, L. V., Virology, 21, 353 (1963).

    Article  Google Scholar 

  33. Russel, W. C., and Crawford, L. V., Virology, 22, 288 (1964).

    Article  CAS  Google Scholar 

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HAUSEN, H., SCHULTE-HOLTHAUSEN, H. Presence of EB Virus Nucleic Acid Homology in a “Virus-free” Line of Burkitt Tumour Cells. Nature 227, 245–248 (1970). https://doi.org/10.1038/227245a0

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