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Low Magnesium and Phospholipid Content of Cell Walls of Pseudomonas aeruginosa resistant to Polymyxin

Nature volume 227, pages 1360–1361 (1970)Cite this article

Abstract

THE resistance of the pathogenic bacterium Pseudomonas aeruginosa to chemical inactivation is notorious. P. aeruginosa and related species cause problems in plant pathology1,2, food spoilage3, contamination of pharmaceuticals4,5 and hospital cross-infection6,7. We report here results relating to the mechanism of resistance of this organism which may also have wider significance for Gram-negative bacteria.

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References

  1. Nelson, P. E., and Dickey, R. S., Phytopathol., 56, 154 (1966).

    CAS  Google Scholar 

  2. Ercolani, G. L., and Crosse, J. E., J. Gen. Microbiol., 45, 429 (1966).

    Article  Google Scholar 

  3. Mossell, D. A. A., and Ingram, M., J. Appl. Bact., 18, 232 (1955).

    Article  Google Scholar 

  4. Leading article, Brit. Med. J., 2, 125 (1967).

  5. Brown, M. R. W., Proc. Roy. Soc. Med., 60, 354 (1967).

    CAS  PubMed  Google Scholar 

  6. Rogers, K. B., J. Appl. Bact., 23, 533 (1960).

    Article  Google Scholar 

  7. Lowbury, E. J. L., Brit. J. Plast. Surg., 20, 211 (1967).

    Article  CAS  Google Scholar 

  8. Brown, M. R. W., and Melling, J., J. Gen. Microbiol., 54, 439 (1969).

    Article  CAS  Google Scholar 

  9. Brown, M. R. W., and Melling, J., J. Gen. Microbiol., 59, 263 (1969).

    Article  CAS  Google Scholar 

  10. Ivanov, V., Markov, K. I., Golovinskii, E., and Kharisanova, T., Z. Naturf., 196, 604 (1964).

    Article  Google Scholar 

  11. Newton, B. A., Bact. Revs., 20, 14 (1956).

    ADS  CAS  Google Scholar 

  12. Gray, G. W., and Wilkinson, S. G., J. Appl. Bact., 28, 153 (1965).

    Article  CAS  Google Scholar 

  13. Tempest, D. W., and Strange, R. E., J. Gen. Microbiol., 44, 213 (1966).

    Article  Google Scholar 

  14. Allen, R. J. L., Biochem. J., 34, 858 (1940).

    Article  CAS  Google Scholar 

  15. Bobo, R. A., and Eagon, R. G., Canad. J. Microbiol., 14, 503 (1968).

    Article  CAS  Google Scholar 

  16. Hugo, W. B., and Stretton, R. J., J. Gen. Microbiol., 42, 133 (1966).

    Article  CAS  Google Scholar 

  17. Neskovic, N. M., J. Chromatog., 27, 488 (1967).

    Article  CAS  Google Scholar 

  18. Hancock, I. C., and Meadow, P. M., Biochim. Biophys. Acta, 187, 366 (1969).

    Article  CAS  Google Scholar 

  19. Hayward, A. C., Forsyth, W. G. C., and Roberts, J. B., J. Gen. Microbiol., 20, 510 (1959).

    Article  CAS  Google Scholar 

  20. Law, J. H., and Slepecky, R. A., J. Bact., 82, 33 (1961).

    CAS  PubMed  Google Scholar 

  21. Blackwood, A. C., and Epp, A., J. Bact., 74, 266 (1957).

    CAS  PubMed  Google Scholar 

  22. Hugo, W. B., J. Appl. Bact., 30, 17 (1967).

    Article  CAS  Google Scholar 

  23. Hamilton, W. A., J. Gen. Microbiol., 50, 441 (1968).

    Article  CAS  Google Scholar 

Download references

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Author notes

  1. M. R. W. BROWN

    Present address: Department of Pharmacy, The University of Aston in Birmingham, Gosta Green, Birmingham, 4

Authors and Affiliations

  1. Pharmaceutical Microbiology Group, School of Pharmacy, Bath University, Somerset

    M. R. W. BROWN & W. M. WATKINS

Authors
  1. M. R. W. BROWN
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  2. W. M. WATKINS
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BROWN, M., WATKINS, W. Low Magnesium and Phospholipid Content of Cell Walls of Pseudomonas aeruginosa resistant to Polymyxin. Nature 227, 1360–1361 (1970). https://doi.org/10.1038/2271360a0

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