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Protein-synthesizing Structures associated with Mitochondria

Nature volume 227, pages 133–137 (1970)Cite this article

Abstract

Protein synthesis in HeLa cell mitochondria is associated with a structure sedimenting at 95S. This has some properties in common with bacterial ribosomes but its physicochemical properties are rather different.

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References

  1. Work, T. S., Coote, J. L., and Ashwell, M., Fed. Proc., 27, 5 (1968).

    Google Scholar 

  2. Wagner, R., Science, 163, 1026 (1969).

    Article  ADS  CAS  Google Scholar 

  3. Gibor, A., and Granick, S., Science, 145, 890 (1964).

    Article  ADS  CAS  Google Scholar 

  4. Roodyn, D. B., and Wilkie, D., The Biogenesis of Mitochondria (Methuen, London, 1968).

    Google Scholar 

  5. Nass, M. M. K., Science, 165, 25 (1969).

    Article  ADS  CAS  Google Scholar 

  6. Vesco, C., and Penman, S., Proc. US Nat. Acad. Sci., 62, 218 (1968).

    Article  ADS  Google Scholar 

  7. Rifkin, M., Wood, D., and Luck, D., Proc. US Nat. Acad. Sci., 58, 1025 (1967).

    Article  ADS  CAS  Google Scholar 

  8. Kuntzel, H., and Noll, H., Nature, 215, 1340 (1967).

    Article  ADS  CAS  Google Scholar 

  9. Dure, L., Epler, J., and Barnett, W., Proc. US Nat. Acad. Sci., 58, 1883 (1967).

    Article  ADS  CAS  Google Scholar 

  10. Rogers, P., Preston, B., Titchener, E., and Linnane, A., Biochem. Biophys. Res. Commun., 27, 405 (1967).

    Article  CAS  Google Scholar 

  11. Leon, S., and Mahler, H., Arch. Biochem. Biophys., 126, 305 (1968).

    Article  CAS  Google Scholar 

  12. Dubin, D., and Brown, R., Biochim. Biophys. Acta, 145, 538 (1967).

    Article  CAS  Google Scholar 

  13. Dawid, I., Fed. Proc., 28, 349 (1969).

    Google Scholar 

  14. Vignais, P., Huet, J., and Andre, J., FEBS Letters, 3, 177 (1969).

    Article  CAS  Google Scholar 

  15. Kuntzel, H., Nature, 222, 142 (1969).

    Article  ADS  CAS  Google Scholar 

  16. Linnane, A., and Firkin, F., Biochem. Biophys. Res. Commun., 32, 398 (1968).

    Article  Google Scholar 

  17. Rabinowitz, H., De Salle, L., Sinclair, J., Stirewalt, R., and Swift, H., Fed. Proc., 25, 581 (1966).

    Google Scholar 

  18. Kalf, G., Arch. Biochem. Biophys., 101, 350 (1963).

    Article  CAS  Google Scholar 

  19. Kroon, A., Biochim. Biophys. Acta, 108, 275 (1965).

    Article  CAS  Google Scholar 

  20. Kroon, A., Biochim. Biophys. Acta, 72, 391 (1963).

    Article  CAS  Google Scholar 

  21. Godchaux, W., and Herbert, E., J. Mol. Biol., 21, 537 (1966).

    Article  CAS  Google Scholar 

  22. Beattie, D., Basford, R., and Koritz, S., Biochemistry, 6, 3099 (1967).

    Article  CAS  Google Scholar 

  23. O'Brien, T., and Kalf, G., J. Biol. Chem., 242, 2172, 2180 (1967).

    CAS  PubMed  Google Scholar 

  24. Loeb, J., and Hubby, B., Biochim. Biophys. Acta, 166, 745 (1968).

    Article  CAS  Google Scholar 

  25. Eagle, H., Science, 130, 432 (1959).

    Article  ADS  CAS  Google Scholar 

  26. Zylber, E., Vesco, C., and Penman, S., J. Mol. Biol., 44, 195 (1969).

    Article  CAS  Google Scholar 

  27. Attardi, B., Cravioto, B., and Attardi, G., J. Mol. Biol., 44, 47 (1969).

    Article  CAS  Google Scholar 

  28. Lamb, A., Clark-Walker, G., and Linnane, A., Biochim. Biophys. Acta, 161, 415 (1968).

    Article  CAS  Google Scholar 

  29. Sebald, W., Bucher, T., Olbrick, B., and Kaudewitz, F., FEBS Letters, 1, 235 (1968).

    Article  CAS  Google Scholar 

  30. Salzman, N., Lockart, jun., R., and Sebring, E., Virology, 9, 244 (1959).

    Article  CAS  Google Scholar 

  31. Darnell, J., and Levintow, L., J. Biol. Chem., 235, 74 (1960).

    CAS  PubMed  Google Scholar 

  32. Zimmerman, E., Heeter, M., and Darnell, J., Virology, 19, 400 (1963).

    Article  CAS  Google Scholar 

  33. Holland, J., and Peterson, J., J. Mol. Biol., 8, 556 (1964).

    Article  CAS  Google Scholar 

  34. Penman, S., Scherrer, K., Becker, Y., and Darnell, J., Proc. US Nat. Acad. Sci., 49, 654 (1963).

    Article  ADS  CAS  Google Scholar 

  35. Holland, J., J. Mol. Biol., 8, 574 (1964).

    Article  CAS  Google Scholar 

  36. Bablanian, R., Eggers, H., and Tamm, I., Virology, 26, 100 (1965).

    Article  CAS  Google Scholar 

  37. Penman, S., and Summers, D., Virology, 27, 614 (1965).

    Article  CAS  Google Scholar 

  38. Perry, R., Exptl. Cell. Res., 29, 400 (1963).

    Article  CAS  Google Scholar 

  39. Roberts, V., and Newman, J., J. Mol. Biol., 20, 63 (1966).

    Article  CAS  Google Scholar 

  40. Penman, S., Vesco, C., and Penman, M., J. Mol. Biol., 34, 49 (1968).

    Article  CAS  Google Scholar 

  41. Warner, J., Knopf, P., and Rich, A., Proc. US Nat. Acad. Sci., 49, 122 (1963).

    Article  ADS  CAS  Google Scholar 

  42. Gilbert, W., J. Mol. Biol., 6, 389 (1963).

    Article  CAS  Google Scholar 

  43. Baltimore, D., and Huang, A., Science, 162, 572 (1968).

    Article  ADS  CAS  Google Scholar 

  44. Perry, R., and Kelly, D., J. Mol. Biol., 16, 255 (1966).

    Article  CAS  Google Scholar 

  45. Henshaw, E., J. Mol. Biol., 36, 401 (1968).

    Article  CAS  Google Scholar 

  46. Spirin, A., Belitsina, A., and Lerman, M., J. Mol. Biol., 14, 611 (1965).

    Article  CAS  Google Scholar 

  47. Girard, M., Latham, H., Penman, S., and Darnell, J., J. Mol. Biol., 11, 187 (1965).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Massachusetts Institute of Technology, Department of Biology, 77 Massachusetts Avenue, Cambridge, Massachusetts, 02139

    STANLEY PERLMAN & SHELDON PENMAN

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  1. STANLEY PERLMAN
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  2. SHELDON PENMAN
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PERLMAN, S., PENMAN, S. Protein-synthesizing Structures associated with Mitochondria. Nature 227, 133–137 (1970). https://doi.org/10.1038/227133a0

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