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Chain Initiation in Primitive Protein Synthesis: a 60S Intermediate in the Formation of Active 70S Ribosomes

Nature volume 227, pages 128–133 (1970)Cite this article

Abstract

Assembly of the active complex from subunits and poly U requires uncharged tRNA and involves the formation of a 60S initiation complex which subsequently is converted into the 70S ribosome by addition of the ternary complex of Phe-tRNA, T-factor and GTP.

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Authors and Affiliations

  1. Department of Biological Sciences, Northwestern University, Evanston, Illinois, 60201

    MAX H. SCHREIER & HANS NOLL

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  1. MAX H. SCHREIER
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  2. HANS NOLL
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SCHREIER, M., NOLL, H. Chain Initiation in Primitive Protein Synthesis: a 60S Intermediate in the Formation of Active 70S Ribosomes. Nature 227, 128–133 (1970). https://doi.org/10.1038/227128a0

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