Is “I-DNA” derived from Nuclear DNA ?

Article metrics


On the basis of double radioactive labelling and buoyant density studies, it is concluded that “I-DNA” is not a separate entity from nuclear DNA but may be an artefact derived from it.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Bell, E., Nature, 224, 326 (1969).

  2. 2

    Fromson, D., and Nemer, M., Science, 168, 266 (1970).

  3. 3

    Haley, E. E., Fischer, G. A., and Welch, A. D., Cancer Res., 21, 532 (1961).

  4. 4

    Sibatani, A., Anal. Biochem., 33, 279 (1970).

  5. 5

    Bollum, F. J., in Procedures in Nucleic Acid Research (edit. by Cantoni G. L. and Davies, D. R.), 284 (Harper and Row, New York, 1966).

  6. 6

    Kirby, K. S., and Cook, E. A., Biochem. J., 10, 254 (1967).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

MÜLLER, W., ZAHN, R. & BEYER, R. Is “I-DNA” derived from Nuclear DNA ?. Nature 227, 1211–1212 (1970) doi:10.1038/2271211a0

Download citation

Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.