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Proteins of Rabbit Reticulocyte Ribosomal Subunits

Nature volume 227, pages 1145–1147 (1970)Cite this article

Abstract

BY comparison with those of prokaryotic cells, especially Escherichia coli, little is known about the ribosornes of eukaryotes. The present analysis of ribosomal proteins from rabbit reticulocytes indicates that—in spite of the larger size of the particle and a higher protein content—the number of different proteins is not significantly greater than that in E. coli ribosomes. There may be multiple copies of some proteins and other proteins may be present in only a fraction of the ribosomes. Proteins from both ribosomal subunits are evidently considerably more basic than the corresponding proteins from E. coli subunits.

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References

  1. Spahr, P. F., J. Mol. Biol., 4, 395 (1962).

    Article  CAS  Google Scholar 

  2. Leboy, P. S., Cox, E. C., and Flaks, J. G., Proc. US Nat. Acad. Sci., 52, 1367 (1964).

    Article  ADS  CAS  Google Scholar 

  3. Low, R. B., and Wool, I. G., Science, 155, 330 (1967).

    Article  ADS  CAS  Google Scholar 

  4. Maizel, J. V., Science, 151, 988 (1966).

    Article  ADS  CAS  Google Scholar 

  5. Shapiro, A. L., Vinuela, E., and Maizel, J. V., Biochem. Biophys. Res. Commun., 28, 815 (1967).

    Article  CAS  Google Scholar 

  6. Weber, K., and Osborn, M., J. Biol. Chem., 244, 4407 (1969).

    Google Scholar 

  7. Dunker, A. K., and Rueckert, R. E., J. Biol. Chem., 244, 4407 (1969).

    Google Scholar 

  8. Kaltschmidt Dzionara, M., Donner, D., and Wittmann, H. G., Molec. Gen. Genet., 100, 364 (1967).

    Article  Google Scholar 

  9. Craven, G. R., Voynow, P., Hardy, S. J. S., and Kurland, C. G., Biochemistry, 8, 2906 (1969).

    Article  CAS  Google Scholar 

  10. Hamilton, M. G., Biochim. Biophys. Acta, 134, 473 (1967).

    Article  CAS  Google Scholar 

  11. Hamilton, M. G., and Ruth, M. E., Biochemistry, 8, 851 (1969).

    Article  CAS  Google Scholar 

  12. Fazekas de St. Groth, S., Webster, R. G., and Datyner, A., Biochim. Biophys. Acta, 71, 377 (1963).

    Article  CAS  Google Scholar 

  13. Hamilton, M. G., and Ruth, M. E., Biochemistry, 6, 2585 (1965).

    Article  Google Scholar 

  14. Loening, U. E., J. Mol. Biol., 38, 355 (1968).

    Article  CAS  Google Scholar 

  15. Sanger, F., Brownlee, G. G., and Barrell, B. G., J. Mol. Biol., 13, 373 (1965).

    Article  CAS  Google Scholar 

  16. Fellner, P., and Sanger, F., Nature, 219, 236 (1969).

    Article  ADS  Google Scholar 

  17. Fellner, P., Europ. J. Biochem., 11, 12 (1969).

    Article  CAS  Google Scholar 

  18. Fellner, P., Ehresmann, C., and Ebel, J. P., Nature, 225, 26 (1970).

    Article  ADS  CAS  Google Scholar 

  19. diGirolamo, M., and Cammarano, P., Biochim. Biophys. Acta, 168, 181 (1968).

    Article  CAS  Google Scholar 

  20. Prichard, P. M., Gilbert, J. M., Shafritz, D. A., and Anderson, W. F., Nature, 226, 607 (1970).

    Article  Google Scholar 

  21. Smith, A. E., and Marcker, K. A., Nature, 226, 607 (1970).

    Article  ADS  CAS  Google Scholar 

  22. Brown, J. C., and Smith, A. E., Nature, 226, 610 (1970).

    Article  ADS  CAS  Google Scholar 

  23. Lacroute, F., and Stent, G. S., J. Mol. Biol., 35, 165 (1968).

    Article  CAS  Google Scholar 

  24. Webster, R. E., and Zinder, N. D., J. Mol. Biol., 42, 425 (1969).

    Article  CAS  Google Scholar 

  25. Canfield, R. E., and Anfinsen, C. B., Biochemistry, 2, 1073 (1964).

    Article  Google Scholar 

  26. Dintzis, H. M., Proc. US Nat. Acad. Sci., 47, 247 (1961).

    Article  ADS  CAS  Google Scholar 

  27. Klucis, E. S., and Gould, H. J., Science, 152, 3720 (1966).

    Article  Google Scholar 

  28. Cox, R. A., in Methods of Enzymology (edit. by Grossman, L., and Moldave K.), XIIB (Academic Press, New York and London, 1968).

    Google Scholar 

  29. Ts'o, P. O. P., Bonner, J., and Dintzis, H., Arch. Biochem. Biophys., 76, 225.

  30. Mathias, A. P., and Williamson, R., J. Mol. Biol., 9, 498 (1964).

    Article  CAS  Google Scholar 

  31. Adams, E., Nomograph (Calif. Corp. Biochem. Res., Los Angeles).

  32. Lowry, O. H., Rosebrough, N. J., Farr, R. J., and Randall, R. J., J. Biol. Chem., 193, 265 (1951).

    CAS  Google Scholar 

  33. Petermann, M. L., and Pavlovec, A., J. Biol. Chem., 238, 318 (1963).

    CAS  PubMed  Google Scholar 

  34. Curry, J. B., and Hersh, R. T., Biochem. Biophys. Res. Commun., 6, 415 (1962).

    Article  CAS  Google Scholar 

  35. Work, T. S., J. Mol. Biol., 10, 544 (1964).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Biochemistry, Imperial College, London, SW7

    H. J. GOULD

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  1. H. J. GOULD
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GOULD, H. Proteins of Rabbit Reticulocyte Ribosomal Subunits. Nature 227, 1145–1147 (1970). https://doi.org/10.1038/2271145a0

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