Mechanism of Pyruvate Carboxylase Formation from the Apo-Enzyme and Biotin in a Thermophilic Bacillus

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  • An Erratum to this article was published on 19 September 1970

Abstract

Pyruvate carboxylase is formed by enzyme-catalysed attachment of biotin to an inactive protein precursor. Acetyl-CoA and aspartate allosterically influence this reaction.

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CAZZULO, J., SUNDARAM, T. & KORNBERG, H. Mechanism of Pyruvate Carboxylase Formation from the Apo-Enzyme and Biotin in a Thermophilic Bacillus. Nature 227, 1103–1105 (1970) doi:10.1038/2271103a0

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