Effect of Diameter on the Electrical Constants of Frog Skeletal Muscle Fibres

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THE relatively large electrical capacity of skeletal muscle fibres1,2 is generally attributed to the transverse tubular system which ramifies over the cross-section of the fibre and enlarges the effective area of the surface. From an analysis of the frequency dependence of the impedance, Falk and Fatt3 assigned a capacity of 2.6 µF/cm2 to the surface membrane and 4.1 µF/cm2 to the contribution of the tubules. Gage and Eisenberg4 showed that fibres “detubulated” by the glycerol method had a low frequency capacity of 2.1 µF/cm2 as compared with 5–12 µF/cm2 in normal fibres.

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NAKAJIMA, S., HODGKIN, A. Effect of Diameter on the Electrical Constants of Frog Skeletal Muscle Fibres. Nature 227, 1053–1055 (1970) doi:10.1038/2271053a0

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