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DNA-directed DNA Polymerase Activity in Oncogenic RNA Viruses


Besides having RNA-dependent DNA polymerase activity, oncogenic RNA viruses possess a DNA-directed DNA polymerase which is distinguished from previously described enzymes of this type in preferring double-stranded DNA as template and yielding a principally double-stranded product.

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SPIEGELMAN, S., BURNY, A., DAS, M. et al. DNA-directed DNA Polymerase Activity in Oncogenic RNA Viruses. Nature 227, 1029–1031 (1970).

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