Formation of Viral RNA–DNA Hybrid Molecules by the DNA Polymerase of Sarcoma-Leukaemia Viruses

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Abstract

Viral RNA is the template for the DNA polymerase of the sarcoma-leukaemia viruses: a “natural” RNA-DNA hybrid is formed by the viral DNA polymerase, and a “synthetic” RNA-DNA hybrid is formed by annealing viral RNA with the DNA product of the DNA polymerase reaction.

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ROKUTANDA, M., ROKUTANDA, H., GREEN, M. et al. Formation of Viral RNA–DNA Hybrid Molecules by the DNA Polymerase of Sarcoma-Leukaemia Viruses. Nature 227, 1026–1028 (1970) doi:10.1038/2271026a0

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