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Excretion of Murine Leukaemia Virus

Abstract

THE study of mice experimentally infected with murine leukaemia virus (MuLV) has revealed leukaemogenic activity in the milk, saliva, urine and faeces, and typical MuLV particles in the mammary glands, salivary glands, and pancreas. MuLV has not been demonstrated, however, in the excretions or secretions of naturally infected mice1–3. The development by Hartley et al.4,5 of the complement fixation test for murine leukaemia virus provided a sensitive in vitro assay for MuLV and a practical means for the detection of virus in tissues, mouth swabs and excretions. We report here studies on the isolation of virus from excretions and secretions of naturally infected high leukaemia strains AKR/J, C58/J and SJL/J.

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MYERS, D., MEIER, H., RHIM, J. et al. Excretion of Murine Leukaemia Virus. Nature 226, 849–850 (1970). https://doi.org/10.1038/226849a0

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