Relationship between Mitosis and the Ordered Structure of the Stratum Corneum in Mouse Epidermis

Abstract

THE cells of the stratum corneum of mammalian skin, although usually regarded as being randomly arranged, have been shown to be aligned in regular columns1. This arrangement was suggested to result from a regular pattern of cell migration from the basal layer. The available evidence, however, links cell migration to cell division and suggests that cell division is a random process2.

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References

  1. 1

    Mackenzie, I. C., Nature, 222, 881 (1969).

  2. 2

    Leblond, C. P., Creulich, R. C., and Pereira, J. P. M., Adv. Biol. Skin, 5, 39 (1964).

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    Christophers, E., and Kligman, A. M., J. Invest. Derm., 42, 407 (1964).

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    Iversen, O. H., Bjerknes, R., and Devik, F., Cell Tissue Kinet., 1, 351 (1968).

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MACKENZIE, I. Relationship between Mitosis and the Ordered Structure of the Stratum Corneum in Mouse Epidermis. Nature 226, 653–655 (1970). https://doi.org/10.1038/226653a0

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