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Extract of Ipomoea pes-caprae (Convolvulaceae) antagonistic to Histamine and Jelly-fish Poison


THE creeper, Ipomoea pes-caprae (L.) Roth, of the family Convolvulaceae, which is found in abundance along the warmer seashores of both hemispheres, is used as a medicant in many parts of the world. The leaves are usually used—either boiled for external appfication as an anodyne in colic or rheumatism, or powdered and incorporated in an ointment said to have good local effects on bedsores—but they may also be used as an escharotic in the treatment of ulcers. Previous reports1,2 suggest that the extracts of the plant have no pharmacological effects.


  1. Christensen, B. V., and Reese, S. A., J. Amer. Pharm. Assoc., 27, 195 (1938).

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  2. Cwalina, G. E., and Jenkins, G. L., J. Amer. Pharm. Assoc., 27, 585 (1938).

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  3. Halstead, B. W., in Poisonous and Venomous Marine Animals of the World, 1, 335 (USGPO, Washington, DC, 1965).

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  4. Burger, A., in Medicinal Chemistry, second ed., 581 (Wiley–Interscience., NY, 1960).

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WASUWAT, S. Extract of Ipomoea pes-caprae (Convolvulaceae) antagonistic to Histamine and Jelly-fish Poison. Nature 225, 758 (1970).

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