Abstract
INDIVIDUAL differences in taste sensitivity to phenyl thiocarbamate in human populations, first demonstrated in 1931, were soon shown to be due to segregation at a single autosomal locus1. Although this phenomenon was initially very interesting, its dependence on a synthetic compound relegated it to a laboratory demonstration of single locus determination of perceptual differences. More recent work concerning the antithyroid activity of PTC and similar compounds in several naturally occurring foodstuffs, however, has prompted renewed interest in this phenomenon2.
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KLEIN, T., DEFRIES, J. Similar Polymorphism of Taste Sensitivity to PTC in Mice and Men. Nature 225, 555–557 (1970). https://doi.org/10.1038/225555a0
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DOI: https://doi.org/10.1038/225555a0
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