INTOXICATION with alcohol is frequently associated with diarrhoea, and disturbances of intestinal function have been reported to be common in chronic alcoholics studied shortly after drinking-bouts1–5. Because the normal diet of alcoholics is characteristically poor, it is not clear whether the transient malabsorption frequently found can be attributed to a direct toxic effect of ethanol on the small intestine, or to a nutritional deficiency. We therefore studied the effects of the experimental ingestion of ethanol in man on vitamin B12 absorption under controlled metabolic ward conditions in the absence of nutritional deficiency.
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LINDENBAUM, J., LIEBER, C. Alcohol-induced Malabsorption of Vitamin B12 in Man. Nature 224, 806 (1969). https://doi.org/10.1038/224806a0
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