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Mechanism of Inhibition of Ribosomes by Streptomycin

Abstract

During streptomycin inhibition of translation of phage mRNA the peptidyl-tRNA is blocked in the ribosome P site. The binding of both aminoacyl-tRNA and peptidyl-tRNA to the ribosomal A site is impaired.

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MODOLELL, J., DAVIS, B. Mechanism of Inhibition of Ribosomes by Streptomycin. Nature 224, 345–348 (1969). https://doi.org/10.1038/224345a0

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  • DOI: https://doi.org/10.1038/224345a0

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