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Toxicity of Interferon Inducers of the Double Stranded RNA Type

Nature volume 224, pages 1023–1024 (1969)Cite this article

Abstract

INTERFERON inducers seem to be the most practical way of making use of interferons in clinical practice. Helenine1 obtained from a fungus Penicillium funiculosum is a powerful interferon inducer and Lampson et al.2 found that the activity was present in a fraction consisting of double stranded RNA. Other double stranded RNA inducers have been discovered, for example, that from Escherichia coli infected with RNA bacteria virus MS2 (ref. 3) and also certain copolymers of synthetic polyribonucleotides.

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References

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Authors and Affiliations

  1. ICI Pharmaceuticals Division, Alderley Park, Macclesfield, Cheshire

    B. J. LEONARD, E. ECCLESTON & D. JONES

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  1. B. J. LEONARD
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  2. E. ECCLESTON
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  3. D. JONES
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LEONARD, B., ECCLESTON, E. & JONES, D. Toxicity of Interferon Inducers of the Double Stranded RNA Type. Nature 224, 1023–1024 (1969). https://doi.org/10.1038/2241023a0

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