In vivo and in vitro Effects of Anti-macrophage Serum

Abstract

PASSAGE through macrophages is necessary if certain antigens are to be immuriogenic1–7, which suggests that anti-macrophage serum (AMS) may interfere with immunological response as does anti-lymphocyte serum. In mice treated with AMS, however, antibody synthesis is not inhibited8,9. This article reports preliminary findings of the effect of AMS on macrophages of mice and on antibody synthesis induced with sheep red blood cells (SRBC) and diphtheria toxoid (DT).

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DESPONT, J., CRUCHAUD, A. In vivo and in vitro Effects of Anti-macrophage Serum. Nature 223, 838–839 (1969). https://doi.org/10.1038/223838a0

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