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In vivo and in vitro Effects of Anti-macrophage Serum

Abstract

PASSAGE through macrophages is necessary if certain antigens are to be immuriogenic1–7, which suggests that anti-macrophage serum (AMS) may interfere with immunological response as does anti-lymphocyte serum. In mice treated with AMS, however, antibody synthesis is not inhibited8,9. This article reports preliminary findings of the effect of AMS on macrophages of mice and on antibody synthesis induced with sheep red blood cells (SRBC) and diphtheria toxoid (DT).

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References

  1. Fishman, M., J. Exp. Med., 114, 837 (1961).

    Article  CAS  Google Scholar 

  2. Fishman, M., and Adler, F. L., J. Exp. Med., 117, 595 (1963).

    Article  CAS  Google Scholar 

  3. Askonas, B. A., and Rhodes, J. M., Nature, 205, 470 (1965).

    Article  ADS  CAS  Google Scholar 

  4. Gallily, R., and Feldman, M., Immunology, 12, 197 (1967).

    CAS  PubMed  PubMed Central  Google Scholar 

  5. Gallily, R., and Garvey, J. S., J. Immunol., 101, 924 (1968).

    CAS  PubMed  Google Scholar 

  6. Unanue, E. R., and Askonas, B. A., J. Exp. Med., 127, 915 (1968).

    Article  CAS  Google Scholar 

  7. Unanue, E. R., and Askonas, B. A., Immunology, 15, 287 (1968).

    CAS  PubMed  PubMed Central  Google Scholar 

  8. Unanue, E. R., Nature, 218, 36 (1968).

    Article  ADS  CAS  Google Scholar 

  9. Loewi, G., Temple, A., Nind, A. P. P., and Axelrad, M., Immunology., 16, 99 (1969).

    CAS  PubMed  PubMed Central  Google Scholar 

  10. Panijel, J., and Cayeux, P., Immunology, 14, 769 (1968).

    CAS  PubMed  PubMed Central  Google Scholar 

  11. Jennings, J. F., and Hughes, L. A., Nature, 221, 79 (1969).

    Article  ADS  CAS  Google Scholar 

  12. Gershon, H., and Feldman, M., Immunology, 15, 827 (1968).

    CAS  PubMed  PubMed Central  Google Scholar 

  13. Eidinger, D., Kahn, S. A., and Millar, K. G., J. Exp. Med., 128, 1183 (1968).

    Article  CAS  Google Scholar 

Download references

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DESPONT, J., CRUCHAUD, A. In vivo and in vitro Effects of Anti-macrophage Serum. Nature 223, 838–839 (1969). https://doi.org/10.1038/223838a0

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  • DOI: https://doi.org/10.1038/223838a0

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