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Two Types of Tubules containing only Sertoli Cells in Adults with Klinefelter's Syndrome

Nature volume 223, pages 643–645 (1969)Cite this article

Abstract

THE tubules in the adult testis are characteristically totally hyalinized in Klinefelter's syndrome. But non-hyalinized tubules are often found in biopsies of reasonable size. Spermatogenesis may occasionally be present2–8, but most tubules only contain Sertoli cells1. I have now found two types of non-hyalinized tubules without spermatogenesis in adult Klinefelter testis. I consider this to be general for this syndrome.

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References

  1. Overzier, C., in Die Intersexualität (edit. by Overzier, C.), 283 (Georg Thieme, Stuttgart, 1961).

    Google Scholar 

  2. Bunge, R. G., and Bradbury, J. T., J. Urol., 76, 758 (1956).

    Article  Google Scholar 

  3. Grumbach, H. M., Blanc, W. R., and Engle, E. T. J. Clin. Endocrinol., 17, 703 (1957).

    Article  CAS  Google Scholar 

  4. Witschi, E., Nelson, W. O., and Segal, S. J. J. Clin. Endocrinol., 17, 737 (1957).

    Article  CAS  Google Scholar 

  5. Ferguson-Smith, M. A., and Munro, I. B., Scot. Med. J., 3, 39 (1958).

    Article  CAS  Google Scholar 

  6. Steinberger, E., Smith, K. D., and Perloff, W. H., J. Clin. Endocrinol., 25, 1325 (1965).

    Article  CAS  Google Scholar 

  7. Futterweit, W., Fertil. Steril., 18, 492 (1967).

    Article  CAS  Google Scholar 

  8. Skakkebæk, N. E., Philip, J., and Hammen, R., Nature, 221, 1075 (1969).

    Article  ADS  Google Scholar 

  9. De la Baize, F. A., Arrillaga, F. C., Irazu, J., and Mancini, R. E., J. Clin. Endocrinol., 12, 1426 (1952).

    Article  Google Scholar 

  10. Johnsen, S. G., Acta Endocrinol., Suppl.,124, 17 (1967).

    Article  Google Scholar 

  11. Frøland, A., thesis, Univ. Copenhagen (in the press).

Download references

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Authors and Affiliations

  1. Cytogenetic Laboratory, Department of Obstetrics and Gynaecology A–I, Rigshospitalet, University Hospital, Copenhagen

    N. E. SKAKKEBÆK

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  1. N. E. SKAKKEBÆK
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SKAKKEBÆK, N. Two Types of Tubules containing only Sertoli Cells in Adults with Klinefelter's Syndrome. Nature 223, 643–645 (1969). https://doi.org/10.1038/223643a0

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