Ion Exchanger from Pearl-shaped Cellulose Gel


WE have described a cellulose gel which allows chromatographic separation of mixtures of high molecular weight substances1. It was obtained from cellulose solutions suspended as droplets in an organic solvent. These beads have a rigid structure and they permit diffusion of very large molecules. We also prepared basic and acidic derivatives as possible ion exchangers for proteins. For this purpose cellulose was reacted with 1-chloro-2-diethyl-amino-ethane, α-chloroacetate or propane-sultone.

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  1. 1

    Determann, H., Rehner, H., and Wieland, Th., Makromol. Chem., 114, 263 (1968).

  2. 2

    Peterson, E. A., and Sober, H. A., J. Amer. Chem. Soc., 76, 1711 (1954): 78, 751 (1956).

  3. 3

    Beisenherz, G., Boltze, J. H., Bücher, Th., Czok, B., Gatbade, K. H., Meyer-Arendt, E., and Pfleiderer, G., Z. Naturforsch., 86, 555 (1953).

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DETERMANN, H., MEYER, N. & WIELAND, T. Ion Exchanger from Pearl-shaped Cellulose Gel. Nature 223, 499–500 (1969).

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