Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Chloroma Regression induced by the Granulocytic Chalone

Nature volume 222, pages 995–996 (1969)Cite this article

Abstract

IT has been demonstrated recently that in four different malignant tumours cells responded by mitotic inhibition to their own tissue-specific chalone when the chalone content was artificially increased either in vitro or in vivo1–3. It has also been shown that when extracts containing melanocyte chalone1 were injected into animals bearing malignant melanomata, the tumours regressed3. We have tried to treat malignant chloroma in rats by means of the granulocytic chalone.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Bullough, W. S., and Laurence, E. B., Nature, 220, 134 and 137 (1968); Europ. J. Cancer, 4, 587, 607 (1968).

    Article  ADS  CAS  Google Scholar 

  2. Rytömaa, T., and Kiviniemi, K., Nature, 220, 136 (1968); Europ. J. Cancer, 4, 595 (1968).

    Article  ADS  Google Scholar 

  3. Mohr, U., Althoff, J., Kinzel, V., Süss, R., and Volm, M., Nature, 220, 138 (1968).

    Article  ADS  CAS  Google Scholar 

  4. Moloney, W. C., Dorr, A. D., Dowd, G., and Boschetti, A. E., Blood, 19, 45 (1962). Weinstein, R. S., and Moloney, W. C., Proc. Soc. Exp. Biol., 118, 459 (1965). Moloney, W. C., and Maniatis, A., Proc. Tenth Cong. Europ. Soc. Haematol., II, 576 (Karger, Basel and New York, 1967). Rosenthal, D. S., and Moloney, W. C., Proc. Soc. Exp. Biol., 126, 682 (1967).

    Google Scholar 

  5. Rytömaa, T., and Kiviniemi, K., Cell Tissue Kinet., 1, 329, 341 (1968).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. II Department of Pathology, University of Helsinki, Helsinki, Finland

    T. RYTÖMAA & KYLLIKKI KIVINIEMI

Authors
  1. T. RYTÖMAA
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. KYLLIKKI KIVINIEMI
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

RYTÖMAA, T., KIVINIEMI, K. Chloroma Regression induced by the Granulocytic Chalone. Nature 222, 995–996 (1969). https://doi.org/10.1038/222995a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/222995a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing