Letter | Published:

Activator of Plasminogen in Saline Extracts of Human Thrombi

Nature volume 222, pages 988990 (07 June 1969) | Download Citation

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Abstract

SINCE the discovery of an activator of plasminogen in animal tissues1, and in saline extracts of human tissues2, its presence in endothelial cells of human veins has been convincingly demonstrated many times3–6. Todd7 has also shown focal areas on plasminogen activator activity in fibrinolysis autographs of human thrombi. Our purpose here is to describe the nature and properties of an activator of plasminogen found in saline extracts of human thrombi, which appears to have a separate identity from other known activators.

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Author information

Author notes

    • P. M. DALAL

    Present address: T. N. Medical College, Bombay 8, India.

Affiliations

  1. Department of Haematology, Radcliffe Infirmary, Oxford.

    • P. M. DALAL
    • , P. M. SHAH
    • , M. J. ALLINGTON
    •  & A. A. SHARP

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DOI

https://doi.org/10.1038/222988a0

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