Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Double-stranded RNA in Vaccinia Virus Infected Cells

Abstract

Double-stranded RNA has been isolated from chick cells and chick cells infected with vaccinia virus. The double-stranded vaccinia virus RNA induces production of interferon.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Ho, M., in Interferons (edit. by Finter, N. B.), 21 (North–Holland Publishing Co., Amsterdam, 1967).

    Google Scholar 

  2. Lampson, G. P., Tytell, A. A., Field, A. K., Nemes, M. N., and Hilleman, M. R., Proc. US Nat. Acad. Sci., 58, 782 (1967).

    Article  ADS  CAS  Google Scholar 

  3. Tytell, A. A., Lampson, G. P., Field, A. K., and Hilleman, M. R., Proc. US Nat. Acad. Sci., 58, 1719 (1967).

    Article  ADS  CAS  Google Scholar 

  4. Field, A. K., Lampson, G. P., Tytell, A. A., Nemes, M. N., and Hilleman, M. R., Proc. US Nat. Acad. Sci., 58, 2102 (1967).

    Article  ADS  CAS  Google Scholar 

  5. Field, A. K., Tytell, A. A., Lampson, G. P., and Hilleman, M. R., Proc. US Nat. Acad. Sci., 58, 1004 (1967).

    Article  ADS  CAS  Google Scholar 

  6. Field, A. K., Tytell, A. A., Lampson, G. P., and Hilleman, M. R., Proc. US Nat. Acad. Sci., 61, 34 (1968).

    Article  Google Scholar 

  7. Vilcek, J., Ng, Mun H., Friedman-Kien, A. E., and Krawciw, T., J. Virol., 2, 648 (1968).

    CAS  PubMed  PubMed Central  Google Scholar 

  8. Finkelstein, M. S., Bausek, G. H., and Merigan, T. C., Science, 161, 465 (1968).

    Article  ADS  CAS  PubMed  Google Scholar 

  9. Younger, J. S., and Hallum, J. V., Virology, 35, 177 (1968).

    Article  Google Scholar 

  10. Dianzani, F., Cantagalli, P., Gagnoni, S., and Rita, G., Proc. Soc. Exp. Biol. and Med., 128, 707 (1968).

    Article  Google Scholar 

  11. Colby, C., and Chamberlin, M. J., Proc. US Nat. Acad. Sci. (in the press).

  12. Joklik, W. K., Biochim. Biophys. Acta, 61, 290 (1962).

    CAS  PubMed  Google Scholar 

  13. Rein, A., and Rubin, H., Exp. Cell Res., 49, 666 (1968).

    Article  CAS  PubMed  Google Scholar 

  14. Gillespie, D., and Spiegelman, S., J. Mol. Biol., 12, 829 (1965).

    Article  CAS  PubMed  Google Scholar 

  15. Westphal, H., and Dulbecco, R., Proc. US Nat. Acad. Sci., 59, 1158 (1968).

    Article  ADS  CAS  Google Scholar 

  16. Carver, D. H., and Marcus, P. I., Virology, 32, 247 (1967).

    Article  CAS  PubMed  Google Scholar 

  17. Geiduschek, E. P., Moohr, F. W., and Weiss, S. G., Proc. US Nat. Acad. Sci., 48, 1078 (1962).

    Article  ADS  CAS  Google Scholar 

  18. Nygaard, A. P., and Hall, B. D., J. Mol. Biol., 9, 125 (1964).

    Article  CAS  PubMed  Google Scholar 

  19. Yankofsky, S. A., and Spiegelman, S., Proc. US Nat. Acad. Sci., 48, 1069 (1962).

    Article  ADS  CAS  Google Scholar 

  20. Montagnier, L., CR Acad. Sci., 267, 1417 (1968).

    CAS  Google Scholar 

  21. Duesberg, P. H., and Robinson, W. S., J. Mol. Biol., 25, 383 (1967).

    Article  CAS  Google Scholar 

  22. Szybalsky, W., Methods in Enzymology, 12B, 330 (1968).

    Article  Google Scholar 

  23. Martin, R. S., and Ames, B. N., J. Biol. Chem., 236, 1372 (1961).

    CAS  PubMed  Google Scholar 

  24. Franklin, R. M., J. Virol., 1, 64 (1967).

    CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

COLBY, C., DUESBERG, P. Double-stranded RNA in Vaccinia Virus Infected Cells. Nature 222, 940–944 (1969). https://doi.org/10.1038/222940a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/222940a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing