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Influence of Germ-free Status on Hepatoma Induction by 7,12-Dimethylbenz(a)anthracene in C3H Mice

Abstract

THE susceptibility of C3H male mice to the apparently spontaneous development of hepatomas has long been recognized1. Castration reduces the incidence of these tumours2 and a high protein diet increases it3.

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GRANT, G., ROE, F. Influence of Germ-free Status on Hepatoma Induction by 7,12-Dimethylbenz(a)anthracene in C3H Mice. Nature 222, 1282–1283 (1969). https://doi.org/10.1038/2221282a0

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