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Amino and Carboxy-terminal Sequences of Ovine Lactogenic Hormone

Nature volume 222, pages 1268–1269 (1969)Cite this article

Abstract

LACTOGENIC hormone (prolactin) isolated from sheep pituitary glands is a protein of molecular weight1,2 24,000 with threonine at the NH2-terminus3 and half-cystine at the COOH-terminus4. It has six half-cystine and seven methionine residues5. We report here the structure of the NH2-terminal sequence, consisting of twenty-four amino-acids as well as six amino-acid residues at the COOH-terminus of the hormone.

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Author notes

  1. TUNG-BIN LO: On leave from Department of Chemistry, National Taiwan University, Formosa.

Authors and Affiliations

  1. Hormone Research Laboratory, University of California, San Francisco, California

    CHOH HAO LI, JONATHAN S. DIXON, KNUD D. SCHMIDT, YURI A. PANKOV & TUNG-BIN LO

  2. Nordisk Insulinlaboratorium, Department of Biochemistry, 2, Ved Stadion, Gentofte, Denmark

    KNUD D. SCHMIDT

  3. Institute of Endocrinology and Hormone Chemistry of the USSR Academy of Medical Sciences, Moscow

    YURI A. PANKOV

Authors
  1. CHOH HAO LI
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  2. JONATHAN S. DIXON
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  3. KNUD D. SCHMIDT
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  4. YURI A. PANKOV
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  5. TUNG-BIN LO
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LI, C., DIXON, J., SCHMIDT, K. et al. Amino and Carboxy-terminal Sequences of Ovine Lactogenic Hormone. Nature 222, 1268–1269 (1969). https://doi.org/10.1038/2221268a0

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