Abstract
THREE molecular species of aldolase have been observed in mammalian tissues: aldolase A in muscle, aldolase B in liver and aldolase C in brain1–3. We have already reported that the aldolase B found in the normal rat liver disappeared in the fast growing and highly malignant rat hepatomas and, instead, aldolase A was produced. In slowly growing rat hepatomas, aldolase A, aldolase B and their hybrids were observed4. The existence of aldolase C in the brain attracted our attention and led us to investigate the aldolase isozyme patterns of human brain tumours.
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SUGIMURA, T., SATO, S., KAWABE, S. et al. Aldolase C in Brain Tumour. Nature 222, 1070 (1969). https://doi.org/10.1038/2221070a0
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DOI: https://doi.org/10.1038/2221070a0
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