Letter | Published:

Interrelationship between Plasma Luteinizing Hormone and Oestradiol in the Human Menstrual Cycle

Naturevolume 222page1063 (1969) | Download Citation



OESTROGENS have a feedback action on the central nervous system1. They are implicated in the regulation of human luteinizing hormone (HLH), high concentrations of oestrogen being associated with low concentrations of HLH and vice versa2.

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    Harris, G. W., in The Pituitary Gland, 2 (edit. by Harris G. W., and Donova, B. T.), 99 (Butterworth, London, 1966).

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    Brown, J. B., Klopper, A., and Loraine, J. A., J. Endocrinol., 17, 401 (1958).

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    Burger, H. G., Catt, K. J., and Brown, J. B., J. Clin. Endocrinol., 28, 1508 (1968).

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    Naftolin, F., Espeland, D., Tremann, J. A., Dillard, E. A., and Paulsen, C. A., in Gonadotrophins 1968 (edit. by Rosemberg, E.) (Geron-x, Los Altos, California, 1968).

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    Corker, C. S., and Exley, D., J. Endocrinol., 43, XXX (1969).

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    Siegel, S., in One Tailed Binomial Test in Nonparametric Statistics for Behavioural Sciences, 36 (McGraw-Hill, New York, 1956).

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  1. MRC Neuroendocrinology Unit, Department of Human Anatomy, University of Oxford

    • C. S. CORKER
    • , F. NAFTOLIN
    •  & D. EXLEY


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