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Antibody Formation in Persistent Tolerant Infection with Lymphocytic Choriomeningitis Virus

Abstract

Antibody to lymphocytic choriomeningitis virus has been detected by the fluorescent antibody technique in mice in a state of persistent tolerant infection.

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References

  1. Burent, F. M., and Fenner, F., The Prodution of Antibodies, second ed. Monograph of the Walter and Eliza Hall Institute, 142 (Macmillan, New York 1949).

    Google Scholar 

  2. Traub, E., J. Exp. Med., 63, 874 (1936).

    Google Scholar 

  3. Hotchin, J., Cold Spring Harbor Sump. Quant. Biol., 27, 479 (1962).

    Article  CAS  Google Scholar 

  4. Hotchin, J., Benson, L. M., and Seamer, J., Virology, 18, 71 (1962).

    Article  Google Scholar 

  5. Hotchin, J., and Benson, L. M., J. Immunol., 91, 460 (1963).

    CAS  PubMed  Google Scholar 

  6. Rowe, W. P., Research Rep. Naval Med. Research Inst., 12, 167 (1954).

    Google Scholar 

  7. Weigand, H., and Hotchin, J., J. Immunol., 86, 401 (1961).

    CAS  Google Scholar 

  8. Hotchin, J., and Collins, D. N., Nature, 203, 1357 (1964).

    Article  ADS  CAS  Google Scholar 

  9. Hotchin, J., NINDB Monograph No. 2, Slow, Latent, and Temperate Virus Infections, 341–359 (1965).

  10. Baker, F. D., and Hotchin, J., Science, 158, 502 (1967).

    Article  ADS  CAS  Google Scholar 

  11. Oldstone, M. B. A., and Dixon, F. J., Science, 158, 1193 (1967).

    Article  ADS  CAS  Google Scholar 

  12. Hirsch, M. S., Murphy, F. A., and Hicklin, M. D., J. Exp. Med., 127, 757 (1968).

    Article  CAS  Google Scholar 

  13. Hotchin, J., Benson, L., and Sikora, E., J. Immunol. (in the press).

  14. Cohen, S. M., Triandaphilli, I. A., Barlow, J. L., and Hotchin, J., J. Immunol., 96, 777 (1966).

    CAS  PubMed  Google Scholar 

  15. Benda, R., Hronovský, V., Červa, L., and Činátl, J., Acta Virologica, 9, 347 (1965).

    Google Scholar 

  16. Stoker, M., and Macpherson, I., Nature, 203, 1355 (1964).

    Article  ADS  CAS  Google Scholar 

  17. Larsen, J. H., Acta Path. Microbiol. Scandinav., 73, 106 (1968).

    Article  CAS  Google Scholar 

  18. Soothill, J. F., Hayes, K., and Dudgeon, J. A., Lancet, i, 1385 (1966).

  19. Hotchin, J., Benson, L., and Gardner, J., Pediat. Res. (in the press).

  20. Hotchin, J., Lancet, ii, 28 (1966).

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BENSON, L., HOTCHIN, J. Antibody Formation in Persistent Tolerant Infection with Lymphocytic Choriomeningitis Virus. Nature 222, 1045–1047 (1969). https://doi.org/10.1038/2221045a0

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